Florence Duffaud Selected Research

Thrombocytopenia (Thrombopenia)

12/2023	Regorafenib in patients with advanced Ewing sarcoma: results of a non-comparative, randomised, double-blind, placebo-controlled, multicentre Phase II study.
1/2022	Doxorubicin alone versus doxorubicin with trabectedin followed by trabectedin alone as first-line therapy for metastatic or unresectable leiomyosarcoma (LMS-04): a randomised, multicentre, open-label phase 3 trial.
1/2021	Efficacy and safety of regorafenib in patients with metastatic or locally advanced chondrosarcoma: Results of a non-comparative, randomised, double-blind, placebo controlled, multicentre phase II study.
4/2015	Trabectedin in combination with doxorubicin for first-line treatment of advanced uterine or soft-tissue leiomyosarcoma (LMS-02): a non-randomised, multicentre, phase 2 trial.

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Florence Duffaud Research Topics

Disease

37	Neoplasms (Cancer) 12/2023 - 01/2003
31	Sarcoma (Soft Tissue Sarcoma) 12/2023 - 01/2003
13	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2023 - 03/2007
10	Neoplasm Metastasis (Metastasis) 07/2023 - 09/2003
9	Osteosarcoma (Osteogenic Sarcoma) 11/2022 - 12/2007
8	Disease Progression 01/2023 - 04/2015
8	Leiomyosarcoma 01/2022 - 01/2012
7	Pain (Aches) 12/2023 - 11/2004
5	Aggressive Fibromatosis (Desmoid) 12/2023 - 01/2009
5	Neutropenia 01/2022 - 01/2011
5	Head and Neck Neoplasms (Head and Neck Cancer) 01/2017 - 05/2008
4	Thrombocytopenia (Thrombopenia) 12/2023 - 04/2015
4	Chordoma 10/2023 - 01/2009
4	Hypertension (High Blood Pressure) 01/2021 - 01/2016
3	Ewing Sarcoma (Sarcoma, Ewing) 12/2023 - 01/2020
3	Liposarcoma 01/2022 - 04/2016
3	Fatigue 01/2022 - 04/2015
3	Chondrosarcoma 11/2021 - 09/2018
3	Dihydropyrimidine Dehydrogenase Deficiency 01/2017 - 10/2006
2	Asthenia 12/2023 - 01/2021
2	Necrosis 12/2023 - 08/2009
2	Febrile Neutropenia 01/2022 - 04/2015
2	Cardiotoxicity 01/2020 - 06/2019
2	Anorexia 01/2018 - 04/2017
2	Cancer Pain 08/2014 - 03/2012
2	Carcinoma (Carcinomatosis) 12/2009 - 05/2008
2	Breast Neoplasms (Breast Cancer) 09/2003 - 02/2003
1	Residual Neoplasm 12/2023
1	Adenosarcoma 07/2023
1	Melanoma (Melanoma, Malignant) 01/2023
1	Death (Near-Death Experience) 01/2023
1	Thyroid Neoplasms (Thyroid Cancer) 01/2023
1	Heart Failure 01/2022
1	COVID-19 01/2022
1	Nausea 01/2022
1	Liver Diseases (Liver Disease) 01/2021
1	Frailty 12/2020
1	Phyllodes Tumor (Cystosarcoma Phylloides) 05/2020
1	Polyploidy 03/2020
1	Rupture 01/2020
1	Pneumothorax 01/2020
1	Hypothyroidism 06/2019
1	Proteinuria 06/2019

Drug/Important Bio-Agent (IBA)

15	Imatinib Mesylate (Gleevec)FDA Link 01/2021 - 01/2003
9	TrabectedinIBA 01/2022 - 02/2013
5	regorafenibIBA 12/2023 - 01/2019
5	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2023 - 02/2013
5	Biomarkers (Surrogate Marker)IBA 12/2020 - 04/2018
5	pazopanib FDA Link 01/2020 - 10/2014
5	Gemcitabine FDA Link 01/2020 - 01/2012
5	Sunitinib (Sutent)FDA Link 08/2019 - 05/2012
4	Analgesics (Analgesic Drugs)IBA 01/2023 - 11/2004
4	Opioid Analgesics (Opioids)IBA 01/2023 - 03/2012
4	Tyrosine Kinase InhibitorsIBA 11/2022 - 08/2012
3	Fluorouracil (Carac)FDA LinkGeneric 01/2017 - 10/2006
3	Capecitabine (Xeloda)FDA Link 01/2011 - 10/2006
2	Indicators and Reagents (Reagents)IBA 01/2023 - 02/2003
2	C-Reactive ProteinIBA 12/2020 - 04/2017
2	Phosphotransferases (Kinase)IBA 03/2020 - 01/2017
2	Messenger RNA (mRNA)IBA 03/2020 - 12/2007
2	Dacarbazine (DIC)FDA LinkGeneric 01/2020 - 04/2016
2	cabozantinibIBA 01/2020 - 10/2014
2	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 08/2006
2	Ifosfamide FDA LinkGeneric 01/2020 - 01/2020
2	palbociclibIBA 08/2019 - 01/2019
2	AntibodiesIBA 01/2018 - 12/2007
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2017 - 08/2012
2	Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA 01/2017 - 10/2006
2	Docetaxel (Taxotere)FDA Link 01/2015 - 01/2012
1	pembrolizumabIBA 10/2023
1	Progesterone Receptors (Progesterone Receptor)IBA 07/2023
1	Estrogen ReceptorsIBA 07/2023
1	Hormones (Hormone)IBA 07/2023
1	Shelterin ComplexIBA 01/2023
1	selinexorIBA 01/2022
1	VaccinesIBA 01/2022
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 12/2020
1	2- benzylidene- 3- (cyclohexylamino)- 2,3- dihydro- 1H- inden- 1- oneIBA 12/2020
1	Alkylating AgentsIBA 05/2020
1	N- (4- ((3- (2- amino- 4- pyrimidinyl)- 2- pyridinyl)oxy)phenyl)- 4- (4- methyl- 2- thienyl)- 1- phthalazinamineIBA 03/2020
1	Aurora KinasesIBA 03/2020
1	Aurora Kinase AIBA 03/2020
1	AnthracyclinesIBA 01/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2020
1	Etoposide (VP 16)FDA LinkGeneric 01/2020
1	Hemoglobins (Hemoglobin)IBA 03/2019
1	AlbuminsIBA 03/2019
1	Carboplatin (JM8)FDA LinkGeneric 03/2019

Therapy/Procedure

22	Drug Therapy (Chemotherapy) 07/2023 - 01/2003
18	Therapeutics 07/2023 - 02/2003
4	Radiotherapy 10/2018 - 01/2015
3	Palliative Care (Palliative Therapy) 08/2018 - 03/2012
2	Adjuvant Chemotherapy 01/2015 - 11/2006
1	Cryotherapy (Therapy, Cold) 12/2023
1	Pain Management 01/2023
1	Activities of Daily Living (ADL) 01/2022
1	Cryosurgery 01/2021
1	Ambulatory Care (Outpatient Care) 12/2020
1	Medication Reconciliation 01/2020
1	Drug Tapering 03/2019